Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-TIMP-1 Antibody (9G112)

🥰Excellent
Catalog No. TMAY-03242

Anti-TIMP-1 Antibody (9G112) is a Rabbit antibody targeting TIMP-1. Anti-TIMP-1 Antibody (9G112) can be used in ELISA.

Anti-TIMP-1 Antibody (9G112)

Anti-TIMP-1 Antibody (9G112)

🥰Excellent
Catalog No. TMAY-03242
Anti-TIMP-1 Antibody (9G112) is a Rabbit antibody targeting TIMP-1. Anti-TIMP-1 Antibody (9G112) can be used in ELISA.
TargetMol
Product information is being updated, if you want to purchase, please click the bulk custom button.
Bulk & Custom
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-TIMP-1 Antibody (9G112) is a Rabbit antibody targeting TIMP-1. Anti-TIMP-1 Antibody (9G112) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
Clone
9G112
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse TIMP-1 (rM TIMP-1; TMPY-01485; NP_035723.2; Met1-Arg205).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. TIMP-1/TIMP1 is found in fetal and adult tissues. Highest levels are found in bone, lung, ovary and uterus. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this protein encoding gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This encoding gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-1/TIMP1 is Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse TIMP-1 Protein (TMPY-01485)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-TIMP-1 Antibody (9G112) | purchase Anti-TIMP-1 Antibody (9G112) | Anti-TIMP-1 Antibody (9G112) cost | order Anti-TIMP-1 Antibody (9G112)