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2-oxo Clopidogrel
😃Good
Catalog No. T36222Cas No. 109904-27-0
Alias (±)-SR-121683, (±)-2-Oxo clopidogrel
2-oxo Clopidogrel((±)-SR-121683)) is a drug metabolite and thiolactone intermediate of Clopidogrel, which is catalyzed by hepatic cytochrome P450 (P450) enzymes via CYP3A oxidation, and is capable of further post hydrolysis to the active metabolite CAM.Clopidogrel is an antithrombotic pro-drug.
2-oxo Clopidogrel
😃Good
Catalog No. T36222Alias (±)-SR-121683, (±)-2-Oxo clopidogrelCas No. 109904-27-0
2-oxo Clopidogrel((±)-SR-121683)) is a drug metabolite and thiolactone intermediate of Clopidogrel, which is catalyzed by hepatic cytochrome P450 (P450) enzymes via CYP3A oxidation, and is capable of further post hydrolysis to the active metabolite CAM.Clopidogrel is an antithrombotic pro-drug.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 μg | $123 | In Stock | |
| 1 mg | $230 | 35 days | |
| 5 mg | $890 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 2-oxo Clopidogrel((±)-SR-121683)) is a drug metabolite and thiolactone intermediate of Clopidogrel, which is catalyzed by hepatic cytochrome P450 (P450) enzymes via CYP3A oxidation, and is capable of further post hydrolysis to the active metabolite CAM.Clopidogrel is an antithrombotic pro-drug. |
| Alias | (±)-SR-121683, (±)-2-Oxo clopidogrel |
| Molecular Weight | 337.82 |
| Formula | C16H16ClNO3S |
| Cas No. | 109904-27-0 |
| Smiles | COC(=O)C(N1CCC2SC(=O)C=C2C1)C1=CC=CC=C1Cl |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 5 mg/mL (14.8 mM), Sonication and heating are recommended. DMSO: 200 mg/mL (592.03 mM), Sonication and heating are recommended. DMF:PBS (pH 7.2) (1:20): < 1 mg/mL, insoluble, Sonication is recommended. DMF: 10 mg/mL (29.6 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||||||||||||
Ethanol/DMF/DMSO
DMF/DMSO
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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