CXCL10 Protein, Rat, Recombinant (His)

Catalog No. TMPY-04943 Copy Product Info

CXCL10 Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10 kDa and the accession number is P48973.

CXCL10 Protein, Rat, Recombinant (His)

Catalog No. TMPY-04943

Copy Product Info

CXCL10 Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10 kDa and the accession number is P48973.

Pack Size	Price	USA Stock	Global Stock
5 μg	$68	-	In Stock
10 μg	$112	-	In Stock
20 μg	$188	-	In Stock
50 μg	$370	7-10 days	7-10 days
100 μg	$716	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CXCL10 Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10 kDa and the accession number is P48973.
Species	Rat
Expression System	P. pastoris (Yeast)
Tag	C-His
Accession Number	P48973
Synonyms	Scyb10,IP-10,chemokine (C-X-C motif) ligand 10
Construction	A DNA sequence encoding the rat CXCL10 (NP_620789.1) (Ile22-Pro98) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ile 22
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	10 kDa (predicted)
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS. PH7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjögren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy