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Anti-AGTR2 Antibody (5P814) (Synonyms: Type 2 angiotensin II receptor, MRX88, MRX 88, ATGR2, ATGR 2, AT2R2|...)
Catalog No. TMAC-00207 Copy Product Info
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Anti-AGTR2 Antibody (5P814) is a Rabbit antibody targeting AGTR2. Anti-AGTR2 Antibody (5P814) can be used in IP,WB.
Anti-AGTR2 Antibody (5P814)
Copy Product Info🥰Excellent
Catalog No. TMAC-00207
Synonyms Type 2 angiotensin II receptor, MRX88, MRX 88, ATGR2, ATGR 2, AT2R2, AT2, AT 2, Angiotensin receptor 2, Angiotensin II type-2 receptor, Angiotensin II Type 2, angiotensin II receptor type 2, AGTR2, AGTR 2
Anti-AGTR2 Antibody (5P814) is a Rabbit antibody targeting AGTR2. Anti-AGTR2 Antibody (5P814) can be used in IP,WB.
Anti-AGTR2 Antibody
(5P814)
(5P814)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-AGTR2 Antibody (5P814) is a Rabbit antibody targeting AGTR2. Anti-AGTR2 Antibody (5P814) can be used in IP,WB. |
| Synonyms | Type 2 angiotensin II receptor, MRX88, MRX 88, ATGR2, ATGR 2, AT2R2, AT2, AT 2, Angiotensin receptor 2, Angiotensin II type-2 receptor, Angiotensin II Type 2, angiotensin II receptor type 2, AGTR2, AGTR 2 |
| Ig Type | IgG |
| Clone | 5P814 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLCγ is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 41 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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