CCR6 Protein-VLP, Human, Recombinant (Flag)

Name: CCR6 Protein-VLP, Human, Recombinant (Flag)
Brand: TargetMol
SKU: TMPY-07064
Rating: 4.5 (1 reviews)

(Synonyms: STRL22, GPR-CY4, GPRCY4, GPR29, DRY-6, DRY6, DCR2, CMKBR6, CKR-L3, CKRL3, CD196, CCR-6, CC-CKR-6, C-C CKR-6, BN-1) Copy Product Info

Synonyms: STRL22, GPR-CY4, GPRCY4, GPR29, DRY-6, DRY6, DCR2, CMKBR6, CKR-L3, CKRL3, CD196, CCR-6, CC-CKR-6, C-C CKR-6, BN-1

Catalog No. TMPY-07064 Copy Product Info

CCR6 Protein-VLP, Human, Recombinant (Flag) is expressed in HEK293 Cells. The accession number is P51684.

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Pack Size	Price	USA Stock	Global Stock
10 µg	$582	7-10 days	7-10 days
20 µg	$983	7-10 days	7-10 days
50 µg	$1,490	7-10 days	7-10 days
100 µg	$2,380	7-10 days	7-10 days
200 µg	$3,590	7-10 days	7-10 days
500 µg	$8,630	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized CCR6 Protein-VLP, Human, Recombinant (Flag) (Cat#TMPY-07064) at 5 μg/mL (100 μL/well) can bind Anti-CCR6 Monoclonal Antibody, Human IgG1, the EC50 is 1-5 ng/mL.
Description	CCR6 Protein-VLP, Human, Recombinant (Flag) is expressed in HEK293 Cells. The accession number is P51684.
Species	Human
Expression System	HEK293 Cells
Tag	N-Flag
Accession Number	P51684
Construction	A DNA sequence encoding the Human CCR6 (P51684) (Met1-Met374) was expressed with a flag tag at the N-terminus.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as sterile 50 mM Hepes, 150 mM NaCl, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Synonyms	STRL22, GPR-CY4, GPRCY4, GPR29, DRY-6, DRY6, DCR2, CMKBR6, CKR-L3, CKRL3, CD196, CCR-6, CC-CKR-6, C-C CKR-6, BN-1
Research Background	Chemokine receptors CCR6 and CCR7 have been reported to play important roles in T cell migration and organ-specific metastasis of various tumors. The expression levels of CCR6 and CCR7 in tumor tissues in patients with lymph node metastases than those without lymph node metastases. CCR6 and CCR7 expressions were also detected in metastatic lymph nodes. CCR6(+) subset of CD4(+) regulatory T cells, a newly characterized subset of Tregs, has been reported to contribute to local immune inhibition. There is a new subset of tumor-resident Tregs, CCR6(+) Tregs, may be dominantly responsible for the immunosuppression in tumor immunity and a potential predictor of the poor prognosis of breast cancer.

Chemical Properties

Molecular Weight

43.49 kDa (predicted)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.