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Anti-5HT7 Receptor Polyclonal Antibody (Synonyms: SR-7, Serotonin receptor 7, Serotonin 5 HT 7 receptor, HTR7...)

Catalog No. TMAB-00013 Copy Product Info
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Anti-5HT7 Receptor Polyclonal Antibody is a Rabbit antibody targeting 5HT7 Receptor. Anti-5HT7 Receptor Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.

Anti-5HT7 Receptor Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-00013
Synonyms SR-7, Serotonin receptor 7, Serotonin 5 HT 7 receptor, HTR7, HT 7, 5-hydroxytryptamine receptor 7, 5-HT-X, 5HT7R, 5-HT-7, 5-HT7, 5HT7, 5 hydroxytryptamine(serotonin) receptor 7(adenylate cyclase coupled), 5 hydroxytryptamine(serotonin) receptor 7, 5 hydroxytryptamine receptor 7, 5 HT X

Anti-5HT7 Receptor Polyclonal Antibody is a Rabbit antibody targeting 5HT7 Receptor. Anti-5HT7 Receptor Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.

Anti-5HT7 Receptor Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-5HT7 Receptor Polyclonal Antibody is a Rabbit antibody targeting 5HT7 Receptor. Anti-5HT7 Receptor Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
SynonymsSR-7, Serotonin receptor 7, Serotonin 5 HT 7 receptor, HTR7, HT 7, 5-hydroxytryptamine receptor 7, 5-HT-X, 5HT7R, 5-HT-7, 5-HT7, 5HT7, 5 hydroxytryptamine(serotonin) receptor 7(adenylate cyclase coupled), 5 hydroxytryptamine(serotonin) receptor 7, 5 hydroxytryptamine receptor 7, 5 HT X
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Sample:
Hippocampus (Mouse) Lysate at 40 μg
Hippocampus (Rat) Lysate at 40 μg
Primary: Anti-5HT7 Receptor (TMAB-00013) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 54 kDa
2. Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Mouse Cerebellum tissue lysates
Lane 3: Rat Cerebrum tissue lysates
Lane 4: Rat Cerebellum tissue lysates
Primary: Anti-5HT7 Receptor (TMAB-00013) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 50 kDa
3. Paraformaldehyde-fixed, paraffin embedded (rat cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (5HT7 Receptor) Polyclonal Antibody, Unconjugated (TMAB-00013) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded (mouse cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (5HT7 Receptor) Polyclonal Antibody, Unconjugated (TMAB-00013) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded (mouse cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (5HT7 Receptor) Polyclonal Antibody, Unconjugated (TMAB-00013) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityIsoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human 5HT7 Receptor/SR-7
Antigen Species
Human
Gene Name
HTR7
Gene ID
Protein Name
5-hydroxytryptamine receptor 7
Uniprot ID
Biology Area
Obesity,Serotonin Receptors
Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
Chemical Properties
Molecular WeightTheoretical: 54 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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