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IGF2BP-2 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00345
Synonyms: IGF-II mRNA-Binding Protein 2, IGF2 mRNA-Binding Protein 2, Hepatocellular Carcinoma Autoantigen p62, IGF2BP2, VICKZ2, IMP-2, VICKZ Family Member 2, IMP2, Insulin-Like Growth Factor 2 mRNA-Binding Protein 2

Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
IGF2BP-2 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 2,070.00
1 mg 5 days $ 2,970.00
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Biological Description
Technical Params
Product Properties
Description Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.
Species Human
Expression System E. coli
Tag C-6His,N-T7 tag
Accession Number Q9Y6M1
Synonyms IGF-II mRNA-Binding Protein 2, IGF2 mRNA-Binding Protein 2, Hepatocellular Carcinoma Autoantigen p62, IGF2BP2, VICKZ2, IMP-2, VICKZ Family Member 2, IMP2, Insulin-Like Growth Factor 2 mRNA-Binding Protein 2
Amino Acid Met1-Thr220
Construction Recombinant Human Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 is produced by our E.coli expression system and the target gene encoding Met1-Thr220 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.
Protein Purity Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 43 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.

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Keywords

IGF2BP-2 Protein, Human, Recombinant (His) VICKZ 2 IGF-II mRNA-Binding Protein 2 VICKZ-2 IGF2 mRNA-Binding Protein 2 Hepatocellular Carcinoma Autoantigen p62 IGF2BP2 IMP 2 VICKZ2 IMP-2 VICKZ Family Member 2 IMP2 Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 recombinant recombinant-proteins proteins protein

 

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