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Pachybasin

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Catalog No. T37267Cas No. 2549-78-2

Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively.

Pachybasin

Pachybasin

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Purity: 99.73%
Catalog No. T37267Cas No. 2549-78-2
Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$70-In Stock
5 mg$157-In Stock
10 mg$232-In Stock
25 mg$355-In Stock
50 mg$497-In Stock
100 mg$666-In Stock
200 mg$898-In Stock
1 mL x 10 mM (in DMSO)$139-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.73%
Appearance:Solid
Color:Yellow
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Product Introduction

Pachybasin AI Summary
Pachybasin exhibits antifungal activity against Botryotinia fuckeliana and Rhizoctonia solani, showing growth inhibition percentages of 6.0% and 13.9% respectively at a concentration of 500 µg/mL. Additionally, it demonstrates antibacterial activity against Bacillus cereus, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, as evidenced by the inhibition zone diameters measured using the agar disk diffusion method..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively.
Chemical Properties
Molecular Weight238.24
FormulaC15H10O3
Cas No.2549-78-2
SmilesCc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Dichloromethane: Soluble
Methanol: Soluble
DMSO: 2.39 mg/mL (10.03 mM), Sonication is recommended.
Ethanol: Soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1974 mL20.9872 mL41.9745 mL209.8724 mL
5 mM0.8395 mL4.1974 mL8.3949 mL41.9745 mL
10 mM0.4197 mL2.0987 mL4.1974 mL20.9872 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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