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L-Ascorbic acid 2-phosphate magnesium

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Catalog No. T19389Cas No. 113170-55-1
Alias 2-Phospho-L-ascorbic acid magnesium

L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) functions as an antioxidant and stimulates hepatocyte growth factor (HGF) production. This long-acting vitamin C derivative promotes collagen formation and expression.

L-Ascorbic acid 2-phosphate magnesium

L-Ascorbic acid 2-phosphate magnesium

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Purity: 99.48%
Catalog No. T19389Alias 2-Phospho-L-ascorbic acid magnesiumCas No. 113170-55-1
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) functions as an antioxidant and stimulates hepatocyte growth factor (HGF) production. This long-acting vitamin C derivative promotes collagen formation and expression.
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500 mg$41In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.48%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) functions as an antioxidant and stimulates hepatocyte growth factor (HGF) production. This long-acting vitamin C derivative promotes collagen formation and expression.
In vitro
L-Ascorbic acid 2-phosphate (50 μM-250 μM) is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 μM AsA2-P and 10 nM dexamethasone (Dex), and 250 μM AsA2-P and 5 nM Dex.L-Ascorbic acid 2-phosphate (0.1-1.5 mM;?2 to 3 weeks with medium exchange every 2 to 3 days) significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) achieves only weak growth stimulation.?A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect.
Synonyms2-Phospho-L-ascorbic acid magnesium
Chemical Properties
Molecular Weight289.53
FormulaC6H9O9P.3/2Mg
Cas No.113170-55-1
SmilesC([C@@H]([C@@H]1C(=C(C(=O)O1)OP(=O)([O-])[O-])O)O)O.[Mg+2]
Relative Density.1.74 g/cm3 at 20℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 20.83 mg/mL (71.94 mM), Sonication is recommended.
DMSO: Slightly soluble
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM3.4539 mL17.2694 mL34.5387 mL172.6937 mL
5 mM0.6908 mL3.4539 mL6.9077 mL34.5387 mL
10 mM0.3454 mL1.7269 mL3.4539 mL17.2694 mL
20 mM0.1727 mL0.8635 mL1.7269 mL8.6347 mL
50 mM0.0691 mL0.3454 mL0.6908 mL3.4539 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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