FGF-21 Protein, Human, Recombinant (His)

Name: FGF-21 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-01889
Rating: 4.5 (1 reviews)

(Synonyms: UNQ3115 / PRO10196, fibroblast growth factor 21) Copy Product Info

Synonyms: UNQ3115 / PRO10196, fibroblast growth factor 21

Catalog No. TMPY-01889 Copy Product Info

FGF-21 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20.2 kDa and the accession number is A0A7U3L5M7.

Pack Size	Price	USA Stock	Global Stock
5 µg	$59	7-10 days	7-10 days
10 µg	$94	7-10 days	7-10 days
20 µg	$155	7-10 days	7-10 days
50 µg	$306	7-10 days	7-10 days
100 µg	$518	7-10 days	7-10 days
200 µg	$858	7-10 days	7-10 days
500 µg	$1,720	7-10 days	7-10 days
1 mg	$3,480	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.1-1 µg/mL in the presence of 2.5 µg/mL of rmKlotho β.
Description	FGF-21 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20.2 kDa and the accession number is A0A7U3L5M7.
Species	Human
Expression System	E. coli
Tag	N-His
Accession Number	Q9NSA1
Construction	A DNA sequence encoding the mature form of human FGF21 (NP_061986.1) (His 29-Ser 209) was expressed, with a polyhistide tag at the N-terminus. Predicted N terminal: Met
Protein Purity	> 95 % as determined by SDS-PAGE
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from 50 mM Tris, 10% glycerol, 0.05% Brij 35, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	UNQ3115 / PRO10196, fibroblast growth factor 21
Research Background	Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.

Chemical Properties

Molecular Weight

20.2 kDa (predicted); 23 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.