Shopping Cart

Your shopping cart is currently empty

Ledipasvir (acetone)

Name: Ledipasvir (acetone)
Brand: TargetMol
SKU: T4203
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4203Cas No. 1441674-54-9

Alias Ledipasvir acetone, GS-5885 acetone

Ledipasvir (acetone) (GS-5885 acetone) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.

Ledipasvir (acetone)

🥰Excellent

Purity: 99.72%

Catalog No. T4203Alias Ledipasvir acetone, GS-5885 acetoneCas No. 1441674-54-9

Ledipasvir (acetone) (GS-5885 acetone) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$30	In Stock	In Stock
5 mg	$68	In Stock	In Stock
10 mg	$89	In Stock	In Stock
25 mg	$158	In Stock	In Stock
50 mg	$259	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$90	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

Questions

Batch Information

Select Batch

Purity:99.72%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Ledipasvir (acetone) (GS-5885 acetone) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.
Targets&IC50	GT1a:34 pM (EC50), GT1b:4 pM(EC50)
Synonyms	Ledipasvir acetone, GS-5885 acetone

Chemical Properties

Molecular Weight	947.08
Formula	C₅₂H₆₀F₂N₈O₇
Cas No.	1441674-54-9
Smiles	CC(C)=O.[H][C@]12CC[C@]([H])(C1)N([C@@H]2c1nc2ccc(cc2[nH]1)-c1ccc2-c3ccc(cc3C(F)(F)c2c1)-c1cnc([nH]1)[C@@H]1CC2(CC2)CN1C(=O)[C@@H](NC(=O)OC)C(C)C)C(=O)[C@@H](NC(=O)OC)C(C)C
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 100 mg/mL (105.59 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 100 mg/mL (105.59 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (4.22 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0559 mL	5.2794 mL	10.5588 mL	52.7939 mL
5 mM	0.2112 mL	1.0559 mL	2.1118 mL	10.5588 mL
10 mM	0.1056 mL	0.5279 mL	1.0559 mL	5.2794 mL
20 mM	0.0528 mL	0.2640 mL	0.5279 mL	2.6397 mL
50 mM	0.0211 mL	0.1056 mL	0.2112 mL	1.0559 mL
100 mM	0.0106 mL	0.0528 mL	0.1056 mL	0.5279 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc