Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) (Synonyms: Phospho-4E-BP1 (T37, 46), PHAS-I, p-4E-BP1 (Thr37,...)
Catalog No. TMAY-01426 Copy Product Info
🥰Excellent
Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) is a Rabbit antibody targeting Phospho-4E-BP1 (Thr37, 46). Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) can be used in WB.
Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153)
Copy Product Info🥰Excellent
Catalog No. TMAY-01426
Synonyms Phospho-4E-BP1 (T37, 46), PHAS-I, p-4E-BP1 (Thr37, 46), p-4E-BP1 (T37, 46), BP-1, 4E-BP1 (p-Thr37, 46), 4E-BP1 (p-T37, 46), 4E-BP1, 4EBP1
Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) is a Rabbit antibody targeting Phospho-4E-BP1 (Thr37, 46). Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) can be used in WB.
Anti-Phospho-4E-BP1
(Thr37, 46) Antibody
(7K153)
(Thr37, 46) Antibody
(7K153)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $80 | 7-10 days | 7-10 days | |
| 100 μL | $235 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) is a Rabbit antibody targeting Phospho-4E-BP1 (Thr37, 46). Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) can be used in WB. |
| Synonyms | Phospho-4E-BP1 (T37, 46), PHAS-I, p-4E-BP1 (Thr37, 46), p-4E-BP1 (T37, 46), BP-1, 4E-BP1 (p-Thr37, 46), 4E-BP1 (p-T37, 46), 4E-BP1, 4EBP1 |
| Ig Type | Rabbit IgG |
| Clone | 7K153 |
| Reactivity | Human;
Species predicted to react based on 100% sequence homology: Mouse, rat |
| Specificity | Human
Species predicted to react based on 100% sequence homology: Mouse, rat |
| Verified Activity | 1. Western blot analysis of extracts from serum-starved HEK293, untreated (line A); treated with IGF1 (100ng/ml, 15min；+) (line B); treated with IGF1 and λ-phosphatase (line C) using Phospho-4E-BP1 (Thr37, 46) rabbit monoclonal Antibody at 1:5000 dilution. (Validation Experiment)
2. Western blot analysis of extracts from HEK293, untreated(line A) or treated with IGF1 (100ng/ml, 15min; +)(line B), using Phospho-4E-BP1 (Thr37, 46) rabbit monoclonal Antibody at 1:5000 dilution (upper) or Anti-4E-BP1 Antibody, Mouse Monoclonal at 1:5000 dilution (lower). |
| Application | |
| Recommended Dose | WB: 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to residues around (Thr37, 46) of Human Phospho-4E-BP1. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcription factor activating transcription factor-4 (ATF4), a master regulator of gene expression in stress responses. 4E-BP1 is characterized by its capacity to bind specifically to eIF4E and inhibit its interaction with eIF4G. Phosphorylation of 4E-BP1 regulates eIF4E availability, and therefore, cap-dependent translation, in cell stress. Binding of eIF4E to eIF4G is inhibited in a competitive manner by 4E-BP1. Phosphorylation of 4E-BP1 decreases the affinity of this protein for eIF4E, thus favouring the binding of eIF4G and enhancing translation. 4E-BP1 is important for beta-cell survival under endoplasmic reticulum (ER) stress. 4E-BP1 mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. Recently, 4E-BP1 was found to be a key factor, which converges several oncogenic signals, phosphorylates the molecules, and drives the downstream proliferative signals. Recent studies showed that high expression of phosphorylated 4E-BP-1 (p-4E-BP1) is associated with poor prognosis, tumor progression, or nodal metastasis in different human cancers. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: residues around (Thr37, 46) of Human Phospho-4E-BP1 |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Calculator
Keywords
Preview
Related Tags: buy Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) | purchase Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) | Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153) cost | order Anti-Phospho-4E-BP1 (Thr37, 46) Antibody (7K153)
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.