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Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 2 (Synonyms: TOP2A (p-Ser1106), TOP2A (p-S1106), p-TOP2A (Ser...)

Catalog No. TMAC-04078 Copy Product Info
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Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TOP2A (Ser1106). Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 2

Copy Product Info
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Catalog No. TMAC-04078
Synonyms TOP2A (p-Ser1106), TOP2A (p-S1106), p-TOP2A (Ser1106), p-TOP2A (S1106)

Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TOP2A (Ser1106). Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-TOP2A
(Ser1106) Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3187-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TOP2A (Ser1106). Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody can be used in IHC,WB.
SynonymsTOP2A (p-Ser1106), TOP2A (p-S1106), p-TOP2A (Ser1106), p-TOP2A (S1106)
Ig Type
IgG
Reactivity
Human,Mouse
Verified Activity
1. Western blot analysis of extracts from Jurkat cells, treated with paclitaxel (1uM, 24hours), using TOP2A (Phospho-Ser1106) antibody TMAC-04078. The lane on the right is treated with the synthesized peptide.
2. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using TOP2A (Phospho-Ser1106) antibody TMAC-04078. The picture on the right is treated with the synthesized peptide.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-3000; IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundControl of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 1106 (E-E-S(p)-D-N) derived from Human TOP2A
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 174 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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