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Anti-PHYH Antibody (2P959)

😃Good
Catalog No. TMAY-02574
Alias RD, phytanoyl-CoA 2-hydroxylase, PHYH1, PAHX, LNAP1, LN1

Anti-PHYH Antibody (2P959) is a Mouse antibody targeting PHYH. Anti-PHYH Antibody (2P959) can be used in ELISA.

Anti-PHYH Antibody (2P959)

Anti-PHYH Antibody (2P959)

😃Good
Catalog No. TMAY-02574Alias RD, phytanoyl-CoA 2-hydroxylase, PHYH1, PAHX, LNAP1, LN1
Anti-PHYH Antibody (2P959) is a Mouse antibody targeting PHYH. Anti-PHYH Antibody (2P959) can be used in ELISA.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-PHYH Antibody (2P959) is a Mouse antibody targeting PHYH. Anti-PHYH Antibody (2P959) can be used in ELISA.
AliasRD, phytanoyl-CoA 2-hydroxylase, PHYH1, PAHX, LNAP1, LN1
Ig Type
Monoclonal Mouse IgG2a
Clone
2P959
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PHYH (rh PHYH; TMPY-03109; O14832; Ser31-Leu338). The IgG fraction of the cell culture supernatant was purified by Protein A affinity.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundPHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. It converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Defects in PHYH can cause Refsum disease (RD). RD is an autosomal recessive disorder characterized clinically by a tetrad of abnormalities: retinitis pigmentosa, peripheral neuropathy, cerebellar ataxia, and elevated protein levels in the cerebrospinal fluid (CSF). Patients exhibit accumulation of the branched-chain fatty acid, phytanic acid, in blood and tissues.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human PHYH protein (TMPY-03109)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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