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APD597

Name: APD597
Brand: TargetMol
SKU: T3176
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3176Cas No. 897732-93-3

Alias JNJ-38431055

APD597 (JNJ-38431055) is a GPR119 agonist, used in the treatment of type 2 diabetes.

APD597

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Purity: 99.78%

Catalog No. T3176Alias JNJ-38431055Cas No. 897732-93-3

APD597 (JNJ-38431055) is a GPR119 agonist, used in the treatment of type 2 diabetes.

Pack Size	Price	Availability
5 mg	$64	In Stock
10 mg	$113	In Stock
25 mg	$179	In Stock
50 mg	$239	In Stock
100 mg	$372	In Stock
1 mL x 10 mM (in DMSO)	$67	In Stock

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Purity:99.78%

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Product Introduction

Bioactivity

Description	APD597 (JNJ-38431055) is a GPR119 agonist, used in the treatment of type 2 diabetes.
Targets&IC50	GPR119 (human):46 nM
Synonyms	JNJ-38431055

Chemical Properties

Molecular Weight	479.55
Formula	C₂₁H₂₉N₅O₆S
Cas No.	897732-93-3
Smiles	COc1c(Nc2ccc(nc2C)S(C)(=O)=O)ncnc1OC1CCN(CC1)C(=O)OC(C)C
Relative Density.	1.311 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (125.12 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0853 mL	10.4264 mL	20.8529 mL	104.2644 mL
5 mM	0.4171 mL	2.0853 mL	4.1706 mL	20.8529 mL
10 mM	0.2085 mL	1.0426 mL	2.0853 mL	10.4264 mL
20 mM	0.1043 mL	0.5213 mL	1.0426 mL	5.2132 mL
50 mM	0.0417 mL	0.2085 mL	0.4171 mL	2.0853 mL
100 mM	0.0209 mL	0.1043 mL	0.2085 mL	1.0426 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc