SNAP is a nitric oxide donor that acts as a stable inhibitor of platelet aggregation. SNAP has played a pivotal role in elucidating nitric oxide–mediated mechanisms in liver fibrosis, hepatic stellate cell phenotype maintenance, and S-nitrosylation pathways in breast cancer models to counteract radiation-induced oxidative stress. SNAP additionally functions as a P-glycoprotein/BCRP inhibitor to enhance radiotracer quantification in rats, while its application as a protease inhibitor in cardiac tissue homogenization has advanced the study of cardiac fibrosis progression and associated biochemical processes.