TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated

Name: TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
Brand: TargetMol
SKU: TMPJ-00255
Rating: 4.5 (1 reviews)

(Synonyms: TGF-β3, TGF-beta3, TGFB3, ARVD) Copy Product Info

Synonyms: TGF-β3, TGF-beta3, TGFB3, ARVD

Catalog No. TMPJ-00255 Copy Product Info

TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P10600.

Pack Size	Price	USA Stock	Global Stock
5 µg	$318	7-10 days	7-10 days
10 µg	$533	7-10 days	7-10 days
20 µg	$900	7-10 days	7-10 days
50 µg	$1,580	7-10 days	7-10 days
100 µg	$2,480	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1. Measured by its ability to inhibit TGF-beta 1 activity on TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.37ng/ml. (Regularly tested) 2. Immobilized Human TGFBR2-Fc at 2μg/ml (100 μl/well)can bind Biotinylated Human TGF-beta 3-Avi . The ED50 of Biotinylated Human TGF-beta 3-Avi is 2.05 ng/ml. (Regularly tested)
Description	TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P10600.
Species	Human
Expression System	HEK293 Cells
Tag	N-Avi
Accession Number	P10600
Amino Acid	Ala301-Ser412
Construction	Ala301-Ser412 (Tyr340Phe)
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 4 mM HCl.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TGF-β3, TGF-beta3, TGFB3, ARVD
Research Background	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. TGF-beta 3 binds with high affinity to TGF-beta RII, a type II serine/threonine kinase receptor. This receptor then phosphorylates and activates type I serine/threonine kinase receptors, TGF-beta RI or ALK-1, to modulate transcription through Smad phosphorylation.

Chemical Properties

Molecular Weight

10-14 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Dose Conversion

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Tech Support

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Keywords

TGFB-3TGFB 3

Related Tags: TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated chemical structure | TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated molecular weight