Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

Fomepizole

🥰Excellent
Catalog No. T0765Cas No. 7554-65-6
Alias Antizol-Vet, Antizol, 4-Methylpyrazole

Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.

Fomepizole
Other Forms of Fomepizole:
Fomepizole hydrochlorideT7224556010-88-9
Backorder
View details

Fomepizole

🥰Excellent
Purity: 99.94%
Catalog No. T0765Alias Antizol-Vet, Antizol, 4-MethylpyrazoleCas No. 7554-65-6
Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
200 mg$30In StockIn Stock
500 mg$46In StockIn Stock
1 g$48-In Stock
1 mL x 10 mM (in DMSO)$51In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.94%
Contact us for more batch information

Resource Download

COA

Product Introduction

Bioactivity
Description
Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
SynonymsAntizol-Vet, Antizol, 4-Methylpyrazole
Chemical Properties
Molecular Weight82.1
FormulaC4H6N2
Cas No.7554-65-6
SmilesCC1=CNN=C1
Relative Density.1.015 g/cm3. Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mg/mL (1218.03 mM), Sonication is recommended.
DMSO: 60 mg/mL (730.82 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (24.36 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM12.1803 mL60.9013 mL121.8027 mL609.0134 mL
5 mM2.4361 mL12.1803 mL24.3605 mL121.8027 mL
10 mM1.2180 mL6.0901 mL12.1803 mL60.9013 mL
20 mM0.6090 mL3.0451 mL6.0901 mL30.4507 mL
50 mM0.2436 mL1.2180 mL2.4361 mL12.1803 mL
100 mM0.1218 mL0.6090 mL1.2180 mL6.0901 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

methanolInhibitorinhibitglycolFomepizoleethylenedehydrogenaseCytochrome P450CYPsCATantidotealcoholADH
Related Tags: buy Fomepizole | purchase Fomepizole | Fomepizole cost | order Fomepizole | Fomepizole chemical structure | Fomepizole formula | Fomepizole molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.