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Sophoricoside

Name: Sophoricoside
Brand: TargetMol
SKU: T3233
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3233Cas No. 152-95-4

Alias Genistein sophoricoside

Sophoricoside (Genistein sophoricoside) is effective against inflammation and can reduce the GPT.

Sophoricoside

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Purity: 98.76%

Catalog No. T3233Alias Genistein sophoricosideCas No. 152-95-4

Sophoricoside (Genistein sophoricoside) is effective against inflammation and can reduce the GPT.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$35	In Stock	In Stock
50 mg	$51	In Stock	In Stock
100 mg	$72	In Stock	In Stock
500 mg	$168	-	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.76%

Appearance:Solid

Color:White

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Sophoricoside AI Summary

Sophoricoside exhibits a range of biological activities. It inhibits cow milk xanthine oxidase by 15.3% at a concentration of 50 µg/mL and demonstrates inhibition of neuraminidase activity in different strains of Influenza A virus, with IC50 values exceeding 100,000.0 nM. Furthermore, Sophoricoside shows significant anti-inflammatory activity in mouse Y16 cells by inhibiting IL-5 production, with an inhibition rate of 93.8% at 50 µM and an IC50 value of 10,300.0 nM. Additionally, it inhibits IL-5-mediated proliferation of mouse Y16 cells with an IC50 value of 10,600.0 nM, showing a notable inhibition rate of 79.1% at 30 µM after 48 hours, as measured by WST-1 assay. Beyond its anti-IL-5 activity, Sophoricoside also interacts with various molecular targets, exhibiting bioactivities against Human Jumonji Domain Containing 2E (JMJD2E), Aldehyde Dehydrogenase 1 (ALDH1A1), and Human Apurinic/apyrimidinic Endonuclease 1 (APE1), with potency values ranging from 12,589.3 nM to 44,668.4 nM. These varied activities suggest Sophoricoside possesses a multifaceted bioactivity profile, making it a potential candidate for further pharmacological studies..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Sophoricoside (Genistein sophoricoside) is effective against inflammation and can reduce the GPT.
Synonyms	Genistein sophoricoside

Chemical Properties

Molecular Weight	432.38
Formula	C₂₁H₂₀O₁₀
Cas No.	152-95-4
Smiles	OC[C@H]1O[C@@H](OC2=CC=C(C=C2)C2=COC3=CC(O)=CC(O)=C3C2=O)[C@H](O)[C@@H](O)[C@@H]1O
Relative Density.	1.3597 g/cm3 (Estimated)

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (578.2 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3128 mL	11.5639 mL	23.1278 mL	115.6390 mL
5 mM	0.4626 mL	2.3128 mL	4.6256 mL	23.1278 mL
10 mM	0.2313 mL	1.1564 mL	2.3128 mL	11.5639 mL
20 mM	0.1156 mL	0.5782 mL	1.1564 mL	5.7820 mL
50 mM	0.0463 mL	0.2313 mL	0.4626 mL	2.3128 mL
100 mM	0.0231 mL	0.1156 mL	0.2313 mL	1.1564 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc