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Anti-CEACAM6 Antibody-PE (9H394)
🥰Excellent
Catalog No. TMAY-01219P
Anti-CEACAM6 Antibody-PE (9H394) is a PE-conjugated Mouse antibody targeting CEACAM6. Anti-CEACAM6 Antibody-PE (9H394) can be used in FCM.
Anti-CEACAM6 Antibody-PE (9H394)
Anti-CEACAM6 Antibody-PE (9H394)
🥰Excellent
Catalog No. TMAY-01219P
Anti-CEACAM6 Antibody-PE (9H394) is a PE-conjugated Mouse antibody targeting CEACAM6. Anti-CEACAM6 Antibody-PE (9H394) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CEACAM6 Antibody-PE (9H394) is a PE-conjugated Mouse antibody targeting CEACAM6. Anti-CEACAM6 Antibody-PE (9H394) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 9H394 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of human CEACAM6 expression on human whole blood granulocytes. Human whole blood granulocytes were stained with PE-conjugated anti-Human CEACAM6. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM6 / CD66c (rh CEACAM6 / CD66c; TMPY-00971; NP_002474.4; Met1-Gly320) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression. |
| Conjucates | PE |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human CEACAM6 / CD66c protein (TMPY-00971) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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