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Anti-IL-11R alpha/IL-11RA Antibody (7B753)
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Catalog No. TMAY-03080
Alias interleukin 11 receptor subunit α, interleukin 11 receptor subunit alpha, IL11RA
Anti-IL-11R alpha/IL-11RA Antibody (7B753) is a Rabbit antibody targeting IL-11R alpha/IL-11RA. Anti-IL-11R alpha/IL-11RA Antibody (7B753) can be used in ELISA.
Anti-IL-11R alpha/IL-11RA Antibody (7B753)
Anti-IL-11R alpha/IL-11RA Antibody (7B753)
😃Good
Catalog No. TMAY-03080Alias interleukin 11 receptor subunit α, interleukin 11 receptor subunit alpha, IL11RA
Anti-IL-11R alpha/IL-11RA Antibody (7B753) is a Rabbit antibody targeting IL-11R alpha/IL-11RA. Anti-IL-11R alpha/IL-11RA Antibody (7B753) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-IL-11R alpha/IL-11RA Antibody (7B753) is a Rabbit antibody targeting IL-11R alpha/IL-11RA. Anti-IL-11R alpha/IL-11RA Antibody (7B753) can be used in ELISA. |
| Alias | interleukin 11 receptor subunit α, interleukin 11 receptor subunit alpha, IL11RA |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7B753 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL11RA (rM IL11RA; TMPY-01250; NP_001156873.1; Met 1-Gln 367) . |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma. This particular receptor is very similar to the ciliary neurotrophic factor since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus, and three variants encoding two different isoforms have been identified. IL11RA/IL-11RA is a receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11, and CT1 can utilize IL6ST for initiating signal transmission. Defects in IL11RA/IL-11RA are a cause of craniosynostosis and dental anomalies (CRSDA). CRSDA is a disorder characterized by craniosynostosis, maxillary hypoplasia, and dental anomalies, including malocclusion, delayed and ectopic tooth eruption, and/or supernumerary teeth. Some patients also display minor digit anomalies, such as syndactyly and/or clinodactyly. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Mouse IL11RA protein (TMPY-01250) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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