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Anti-NKp30/NCR3 Antibody (8S649) is a Rabbit antibody targeting NKp30/NCR3. Anti-NKp30/NCR3 Antibody (8S649) can be used in WB,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $268 | 7-10 days |
Description | Anti-NKp30/NCR3 Antibody (8S649) is a Rabbit antibody targeting NKp30/NCR3. Anti-NKp30/NCR3 Antibody (8S649) can be used in WB,ELISA. |
Alias | NKp30, NCR3, natural cytotoxicity triggering receptor 3, MALS, LY117, DAAP-90L16.3, CD337, 1C7 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 8S649 |
Reactivity | Human |
Verified Activity | Anti-NCR3 rabbit monoclonal antibody at 1:500 dilution. -Lane A: K562 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:22 kDa. -Observed band size:14 kDa |
Application | WB,ELISA |
Recommended Dose | WB: 1:500-1:1000; ELISA: 1:25000-1:50000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human NCR3 / CD337 (rh NCR3 / CD337; TMPY-01145; NP_667341.1; Met1-Gly135). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive, but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human NCR3 / CD337 Protein (TMPY-01145) |
Antigen Species | Human |
Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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