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Anti-NKp30/NCR3 Antibody (8S649)

😃Good
Catalog No. TMAY-00883
Alias NKp30, NCR3, natural cytotoxicity triggering receptor 3, MALS, LY117, DAAP-90L16.3, CD337, 1C7

Anti-NKp30/NCR3 Antibody (8S649) is a Rabbit antibody targeting NKp30/NCR3. Anti-NKp30/NCR3 Antibody (8S649) can be used in WB,ELISA.

Anti-NKp30/NCR3 Antibody (8S649)

Anti-NKp30/NCR3 Antibody (8S649)

😃Good
Catalog No. TMAY-00883Alias NKp30, NCR3, natural cytotoxicity triggering receptor 3, MALS, LY117, DAAP-90L16.3, CD337, 1C7
Anti-NKp30/NCR3 Antibody (8S649) is a Rabbit antibody targeting NKp30/NCR3. Anti-NKp30/NCR3 Antibody (8S649) can be used in WB,ELISA.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-NKp30/NCR3 Antibody (8S649) is a Rabbit antibody targeting NKp30/NCR3. Anti-NKp30/NCR3 Antibody (8S649) can be used in WB,ELISA.
AliasNKp30, NCR3, natural cytotoxicity triggering receptor 3, MALS, LY117, DAAP-90L16.3, CD337, 1C7
Ig Type
Monoclonal Rabbit IgG
Clone
8S649
Reactivity
Human
Verified Activity
Anti-NCR3 rabbit monoclonal antibody at 1:500 dilution.

-Lane A: K562 Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

-Developed using the Odyssey technique.

-Performed under reducing conditions.

-Predicted band size:22 kDa.

-Observed band size:14 kDa
Application
WB,ELISA
Recommended Dose
WB: 1:500-1:1000; ELISA: 1:25000-1:50000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human NCR3 / CD337 (rh NCR3 / CD337; TMPY-01145; NP_667341.1; Met1-Gly135).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundNatural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive, but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human NCR3 / CD337 Protein (TMPY-01145)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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