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FGF-12 Protein, Human, Recombinant

(Synonyms: Myocyte-Activating Factor, Fibroblast Growth Factor Homologous Factor 1, Fibroblast Growth Factor 12, FHF-1, FHF1, FGF12B, FGF-12, FGF12) Copy Product Info

Synonyms: Myocyte-Activating Factor, Fibroblast Growth Factor Homologous Factor 1, Fibroblast Growth Factor 12, FHF-1, FHF1, FGF12B, FGF-12, FGF12

Catalog No. TMPJ-01041 Copy Product Info
Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
FGF-12 Protein, Human, Recombinant
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$617-10 days7-10 days
10 µg$977-10 days7-10 days
20 µg$1487-10 days7-10 days
50 µg$2727-10 days7-10 days
100 µg$4857-10 days7-10 days
200 µg$8697-10 days7-10 days
500 µg$1,9007-10 days7-10 days
1 mg$2,7307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberP61328-2
Amino AcidMet1-Thr181
ConstructionMet1-Thr181
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 5 mM EDTA, pH 7.5.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsMyocyte-Activating Factor, Fibroblast Growth Factor Homologous Factor 1, Fibroblast Growth Factor 12, FHF-1, FHF1, FGF12B, FGF-12, FGF12
Research Background
Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
Chemical Properties
Molecular Weight19 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: FGF-12 Protein, Human, Recombinant chemical structure | FGF-12 Protein, Human, Recombinant molecular weight