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Abametapir

Name: Abametapir
Brand: TargetMol
SKU: T7459
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7459Cas No. 1762-34-1

Alias HA-44, BRN 0123183

Abametapir (BRN 0123183), a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.

Abametapir

🥰Excellent

Purity: 99.44%

Catalog No. T7459Alias HA-44, BRN 0123183Cas No. 1762-34-1

Abametapir (BRN 0123183), a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.

Pack Size	Price	Availability
1 g	$33	In Stock
2 g	$44	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.44%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Abametapir (BRN 0123183), a metalloproteinase inhibitor, is able to target metalloproteinases critical to egg hatching and louse development.
In vitro	Bbametapir was 100% ovicidal against eggs of all ages when evaluated at a concentration of 0.37 and 0.55%.
Synonyms	HA-44, BRN 0123183

Chemical Properties

Molecular Weight	184.24
Formula	C₁₂H₁₂N₂
Cas No.	1762-34-1
Smiles	Cc1ccc(nc1)-c1ccc(C)cn1
Relative Density.	1.06g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 37 mg/mL (200.83 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (10.86 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.4277 mL	27.1385 mL	54.2770 mL	271.3851 mL
5 mM	1.0855 mL	5.4277 mL	10.8554 mL	54.2770 mL
10 mM	0.5428 mL	2.7139 mL	5.4277 mL	27.1385 mL
20 mM	0.2714 mL	1.3569 mL	2.7139 mL	13.5693 mL
50 mM	0.1086 mL	0.5428 mL	1.0855 mL	5.4277 mL
100 mM	0.0543 mL	0.2714 mL	0.5428 mL	2.7139 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc