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MSPR/Ron Protein, Human, Recombinant (His)

(Synonyms: RON, PTK8, p185-Ron, MST1R, MSPR, MSP receptor, MSP R, CDw136, CD136) Copy Product Info

Synonyms: RON, PTK8, p185-Ron, MST1R, MSPR, MSP receptor, MSP R, CDw136, CD136

Catalog No. TMPK-00634 Copy Product Info
Macrophage-stimulating protein (MSP) is a serum protein belonging to the plasminogen-related growth factor family. The specific receptor for MSP is the RON (recepteur d'origine nantais) receptor tyrosine kinase - a member of the MET proto-oncogene family. Activation of RON by MSP exerts dual functions on macrophages.
MSPR/Ron Protein, Human, Recombinant (His)
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$587-10 days7-10 days
10 µg$927-10 days7-10 days
20 µg$1487-10 days7-10 days
50 µg$2897-10 days7-10 days
100 µg$4877-10 days7-10 days
200 µg$8837-10 days7-10 days
500 µg$1,9507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Human MSPR, His Tag at 1 μg/mL (100 μL/well) on the plate. Dose response curve for Anti-MSPR Antibody, hFc Tag with the EC50 of 2.0 ng/mL determined by ELISA.(QC Test)
Description
Macrophage-stimulating protein (MSP) is a serum protein belonging to the plasminogen-related growth factor family. The specific receptor for MSP is the RON (recepteur d'origine nantais) receptor tyrosine kinase - a member of the MET proto-oncogene family. Activation of RON by MSP exerts dual functions on macrophages.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberCAA49634.1
ConstructionGlu25-Leu571
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsRON, PTK8, p185-Ron, MST1R, MSPR, MSP receptor, MSP R, CDw136, CD136
Research Background
Macrophage-stimulating protein (MSP) is a serum protein belonging to the plasminogen-related growth factor family. The specific receptor for MSP is the RON (recepteur d'origine nantais) receptor tyrosine kinase - a member of the MET proto-oncogene family. Activation of RON by MSP exerts dual functions on macrophages.
Chemical Properties
Molecular Weight59.71 kDa (predicted). Due to furin cleavage, the protein migrates to 70-80 kDa (full length) and 40-50 kDa (alpha chain) and 35-40 kDa (partial beta chain) based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: MSPR/Ron Protein, Human, Recombinant (His) chemical structure | MSPR/Ron Protein, Human, Recombinant (His) molecular weight