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Anti-ADRA2A-VLP Polyclonal Antibody
😃Good
Catalog No. TMAB-00067
Alias Alpha-2A adrenoreceptor (Alpha-2A adrenoceptor;Alpha-2AAR), Alpha-2A adrenergic receptor, Alpha-2 adrenergic receptor subtype C10, ADRAR, ADRA2R, ADRA2A
Anti-ADRA2A-VLP Polyclonal Antibody is a Rabbit antibody targeting ADRA2A-VLP. Anti-ADRA2A-VLP Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-ADRA2A-VLP Polyclonal Antibody
Anti-ADRA2A-VLP Polyclonal Antibody
😃Good
Catalog No. TMAB-00067Alias Alpha-2A adrenoreceptor (Alpha-2A adrenoceptor;Alpha-2AAR), Alpha-2A adrenergic receptor, Alpha-2 adrenergic receptor subtype C10, ADRAR, ADRA2R, ADRA2A
Anti-ADRA2A-VLP Polyclonal Antibody is a Rabbit antibody targeting ADRA2A-VLP. Anti-ADRA2A-VLP Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-ADRA2A-VLP Polyclonal Antibody is a Rabbit antibody targeting ADRA2A-VLP. Anti-ADRA2A-VLP Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | Alpha-2A adrenoreceptor (Alpha-2A adrenoceptor;Alpha-2AAR), Alpha-2A adrenergic receptor, Alpha-2 adrenergic receptor subtype C10, ADRAR, ADRA2R, ADRA2A |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Pig,Cow,Rabbit) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ADRA2) Polyclonal Antibody, Unconjugated (TMAB-00067) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 min and DAB staining.  |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha 2A, alpha 2B, and alpha 2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha 2A and alpha 2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha 2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha 2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha 2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: human ADRA2 |
| Antigen Species | Human |
| Gene Name | ADRA2A |
| Gene ID | |
| Protein Name | alpha-2A adrenergic receptor |
| Uniprot ID | |
| Biology Area | Adrenergic Receptors,GPCR |
| Function | Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. |
| Molecular Weight | Theoretical: 50 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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