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Anti-FSTL1 Antibody (6P946)

😃Good
Catalog No. TMAY-01331
Alias TSC-36, Fstl, follistatin-like 1, AW107808, AI316791

Anti-FSTL1 Antibody (6P946) is a Mouse antibody targeting FSTL1. Anti-FSTL1 Antibody (6P946) can be used in ELISA.

Anti-FSTL1 Antibody (6P946)

Anti-FSTL1 Antibody (6P946)

😃Good
Catalog No. TMAY-01331Alias TSC-36, Fstl, follistatin-like 1, AW107808, AI316791
Anti-FSTL1 Antibody (6P946) is a Mouse antibody targeting FSTL1. Anti-FSTL1 Antibody (6P946) can be used in ELISA.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Mouse Monoclonal

Application: ELISA

Reactivity: Human
AliasTSC-36, Fstl, follistatin-like 1, AW107808, AI316791
Ig Type
Mouse IgG1
Clone
6P946
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human FSTL1 (rh FSTL1; TMPY-01106; NP_009016.1; Met1-Ile308). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundFollistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human FSTL1 Protein (TMPY-01106)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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