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Anti-SIRT3 Polyclonal Antibody
(Synonyms: SIRT3, SIR2-like protein 3, SIR2L3, Regulatory protein SIR2 homolog 3, NAD-dependent protein delactylase sirtuin-3, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, mitochondrial, hSIRT3) Copy Product Info
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Synonyms: SIRT3, SIR2-like protein 3, SIR2L3, Regulatory protein SIR2 homolog 3, NAD-dependent protein delactylase sirtuin-3, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, mitochondrial, hSIRT3
Catalog No. TMAB-01692 Copy Product Info
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Anti-SIRT3 Polyclonal Antibody is a Rabbit antibody targeting SIRT3. Anti-SIRT3 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
Anti-SIRT3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-SIRT3 Polyclonal Antibody is a Rabbit antibody targeting SIRT3. Anti-SIRT3 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P. |
| Synonyms | SIRT3, SIR2-like protein 3, SIR2L3, Regulatory protein SIR2 homolog 3, NAD-dependent protein delactylase sirtuin-3, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, mitochondrial, hSIRT3 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IF=1:50-200; IHC-Fr=1:50-200; IHC-P=1:50-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion matrix. |
| Tissue Specificity | Widely expressed. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019] |
| Immunogen | KLH conjugated synthetic peptide: human SIRT3 |
| Antigen Species | Human |
| Gene Name | SIRT3 |
| Gene ID | |
| Protein Name | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
| Uniprot ID | |
| Biology Area | Tumor suppressors,Cardiac metabolism,Other cell division antibodies,Acetylation,Class III / Sir2 class,Obesity |
| Function | NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. |
| Molecular Weight | Theoretical: 28/43 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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