Anti-Transferrin Receptor/TFRC Antibody (5P550)

Name: Anti-Transferrin Receptor/TFRC Antibody (5P550)
Brand: TargetMol
SKU: TMAY-01478
Rating: 4.5 (1 reviews)

(Synonyms: transferrin receptor) Copy Product Info

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Synonyms: transferrin receptor

Catalog No. TMAY-01478 Copy Product Info

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Anti-Transferrin Receptor/TFRC Antibody (5P550) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (5P550) can be used in FCM,ICC/IF.

Anti-Transferrin Receptor/TFRC Antibody
(5P550)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 µL	$268	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-Transferrin Receptor/TFRC Antibody (5P550) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (5P550) can be used in FCM,ICC/IF.
Synonyms	transferrin receptor
Ig Type	Rabbit IgG
Clone	5P550
Reactivity	Human
Specificity	Human Transferrin Receptor/TFR1/CD71
Verified Activity	1. Immunofluorescence staining of Human TFRC in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human TFRC monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cytoplasm. 2. Flow cytometric analysis of Human TFRC(CD71) expression on U937 cells. Cells were stained with purified anti-Human TFRC(CD71), then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application	FCM ICC/IF
Recommended Dose	ICC-IF: 1:20-1:100; FCM: 1:25-1:100
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Human Transferrin Receptor / TFRC / CD71 (rh Transferrin Receptor / TFRC / CD71; TMPY-01873; AAA61153.1; Cys89-Phe760).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	APC/PerCP/FITC/PE
Antibody Types Available	5

Antigen Details

Immunogen	Recombinant Protein: Human Transferrin Receptor / TFRC / CD71 protein (TMPY-01873)
Antigen Species	Human

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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