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VH032-PEG5-C6-Cl

Name: VH032-PEG5-C6-Cl
Brand: TargetMol
SKU: T17996
Rating: 4.5 (1 reviews)

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Catalog No. T17996Cas No. 1799506-06-1

Alias HaloPROTAC 2

VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule that includes the VH032-based VHL ligand and a 5-unit PEG linker, capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

VH032-PEG5-C6-Cl

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Catalog No. T17996Alias HaloPROTAC 2Cas No. 1799506-06-1

VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule that includes the VH032-based VHL ligand and a 5-unit PEG linker, capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	Inquiry	Backorder	Backorder
500 mg	Inquiry	Backorder	Backorder

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule that includes the VH032-based VHL ligand and a 5-unit PEG linker, capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
In vitro	Treatment with VH032-PEG5-C6-Cl for 24 hours results in approximately 70% degradation of GFP-Halotag7 at a concentration of 2.5 μM[1].
Synonyms	HaloPROTAC 2

Chemical Properties

Molecular Weight	783.41
Formula	C₃₈H₅₉ClN₄O₉S
Cas No.	1799506-06-1
Relative Density.	1.200 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (63.82 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 5 mg/mL (6.38 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2765 mL	6.3824 mL	12.7647 mL	63.8235 mL
5 mM	0.2553 mL	1.2765 mL	2.5529 mL	12.7647 mL
10 mM	0.1276 mL	0.6382 mL	1.2765 mL	6.3824 mL
20 mM	0.0638 mL	0.3191 mL	0.6382 mL	3.1912 mL
50 mM	0.0255 mL	0.1276 mL	0.2553 mL	1.2765 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc