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Anti-CD8 alpha Antibody-APC (8B814)

🥰Excellent
Catalog No. TMAY-03262A

Anti-CD8 alpha Antibody-APC (8B814) is a APC-conjugated Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody-APC (8B814) can be used in FCM.

Anti-CD8 alpha Antibody-APC (8B814)

Anti-CD8 alpha Antibody-APC (8B814)

🥰Excellent
Catalog No. TMAY-03262A
Anti-CD8 alpha Antibody-APC (8B814) is a APC-conjugated Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody-APC (8B814) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-CD8 alpha Antibody-APC (8B814) is a APC-conjugated Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody-APC (8B814) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
8B814
Reactivity
Mouse
Verified Activity
Flow cytometric analysis of CD8α expression on spleen lymphocytes. BALB/c splenocytes were stained with APC-conjugated anti-Mouse CD8α. The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.
Application
FCM
Recommended Dose
5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD8a (rM CD8a; TMPY-01314; NP_001074579.1; Met1-Tyr196) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundT-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/PerCP/FITC/PE
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Mouse CD8a protein (TMPY-01314)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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