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Anti-Serpin B3 Antibody (3Q78)
😃Good
Catalog No. TMAY-02540
Alias T4-A, serpin peptidase inhibitor, clade B (ovalbumin), member 3, SCCA-PD, SCCA-1, SCCA1, SCC, HsT1196
Anti-Serpin B3 Antibody (3Q78) is a Rabbit antibody targeting Serpin B3. Anti-Serpin B3 Antibody (3Q78) can be used in IP.
Anti-Serpin B3 Antibody (3Q78)
Anti-Serpin B3 Antibody (3Q78)
😃Good
Catalog No. TMAY-02540Alias T4-A, serpin peptidase inhibitor, clade B (ovalbumin), member 3, SCCA-PD, SCCA-1, SCCA1, SCC, HsT1196
Anti-Serpin B3 Antibody (3Q78) is a Rabbit antibody targeting Serpin B3. Anti-Serpin B3 Antibody (3Q78) can be used in IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Serpin B3 Antibody (3Q78) is a Rabbit antibody targeting Serpin B3. Anti-Serpin B3 Antibody (3Q78) can be used in IP. |
| Alias | T4-A, serpin peptidase inhibitor, clade B (ovalbumin), member 3, SCCA-PD, SCCA-1, SCCA1, SCC, HsT1196 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3Q78 |
| Reactivity | Human |
| Verified Activity | SERPINB3 was immunoprecipitated using: -Lane A:0.5 mg A431 Whole Cell Lysate. -4 µL anti-SERPINB3 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-SERPINB3 rabbit monoclonal antibody, at 1:100 dilution. -Secondary antibody: -Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 42 kDa. -Observed band size: 42 kDa |
| Application | IP |
| Recommended Dose | IP: 4-8 μL/mg of lysate |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human SERPINB3 / SCCA-1 (rh SERPINB3 / SCCA-1; TMPY-02712; AAB20405.1; Asn2-Pro390). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be secreted in plasma by cancerous cells but at a low level. SERPINB3 significantly attenuates apoptosis by contrasting cytochrome c release from the mitochondria and by antichemotactic effect for NK cells. It may act as a protease inhibitor to modulate the host immune response against tumor cells and may be involved in the malignant behavior of squamous cell carcinoma cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human SERPINB3 / SCCA-1 Protein (TMPY-02712) |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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