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Anti-Serpin B3 Antibody (3Q78)

(Synonyms: T4-A, serpin peptidase inhibitor, clade B (ovalbumin), member 3, SCCA-PD, SCCA-1, SCCA1, SCC, HsT1196) Copy Product Info
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Synonyms: T4-A, serpin peptidase inhibitor, clade B (ovalbumin), member 3, SCCA-PD, SCCA-1, SCCA1, SCC, HsT1196

Catalog No. TMAY-02540 Copy Product Info
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Anti-Serpin B3 Antibody (3Q78) is a Rabbit antibody targeting Serpin B3. Anti-Serpin B3 Antibody (3Q78) can be used in IP.
Anti-Serpin B3 Antibody
(3Q78)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Serpin B3 Antibody (3Q78) is a Rabbit antibody targeting Serpin B3. Anti-Serpin B3 Antibody (3Q78) can be used in IP.
SynonymsT4-A, serpin peptidase inhibitor, clade B (ovalbumin), member 3, SCCA-PD, SCCA-1, SCCA1, SCC, HsT1196
Ig Type
Rabbit IgG
Clone
3Q78
Reactivity
Human
Specificity
Human SerpinB3
Application
Recommended Dose
IP: 4-8 μL/mg of lysate
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human SERPINB3 / SCCA-1 (rh SERPINB3 / SCCA-1; TMPY-02712; AAB20405.1; Asn2-Pro390).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be secreted in plasma by cancerous cells but at a low level. SERPINB3 significantly attenuates apoptosis by contrasting cytochrome c release from the mitochondria and by antichemotactic effect for NK cells. It may act as a protease inhibitor to modulate the host immune response against tumor cells and may be involved in the malignant behavior of squamous cell carcinoma cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human SERPINB3 / SCCA-1 Protein (TMPY-02712)
Antigen Species
Human
Biology Area
Serine Proteases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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