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Anti-CDCP1 Antibody (2K468) (Synonyms: TRASK, SIMA135, CUB domain containing protein 1, CD318)
Catalog No. TMAY-03550 Copy Product Info
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Anti-CDCP1 Antibody (2K468) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (2K468) can be used in ELISA(Cap).
Anti-CDCP1 Antibody (2K468)
Copy Product Info🥰Excellent
Catalog No. TMAY-03550
Synonyms TRASK, SIMA135, CUB domain containing protein 1, CD318
Anti-CDCP1 Antibody (2K468) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (2K468) can be used in ELISA(Cap).
Anti-CDCP1 Antibody
(2K468)
(2K468)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $93 | 7-10 days | 7-10 days | |
| 100 μL | $270 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CDCP1 Antibody (2K468) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (2K468) can be used in ELISA(Cap). |
| Synonyms | TRASK, SIMA135, CUB domain containing protein 1, CD318 |
| Ig Type | Rabbit IgG |
| Clone | 2K468 |
| Reactivity | Mouse |
| Specificity | Mouse CDCP1 |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CDCP1 (rM CDCP1; TMPY-02901; Q5U462; Met1-Leu666). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migration of ovarian cancer Caov3 and OVCA420 cells with concomitant up-regulation of CDCP1 mRNA and protein. Consistent with a role in cell migration CDCP1 relocates from cell-cell junctions to punctate structures on filopodia after activation of EGFR. It may be involved in cell adhesion and cell matrix association. It also may play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. It has been taken as a novel marker for leukemia diagnosis and immature hematopoietic stem cell subsets. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse CDCP1 Protein (TMPY-02901) |
| Antigen Species | Mouse |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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