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CCR8 Protein, Human, Recombinant (mFc)
(Synonyms: TER-1, TER1, GPR-CY6, GPRCY6, CY6, CMKBRL2, CMKBR8, CKR-L1, CKRL1, ChemR1, CDw198, CD198, CCR-8, CCR8) Copy Product InfoSynonyms: TER-1, TER1, GPR-CY6, GPRCY6, CY6, CMKBRL2, CMKBR8, CKR-L1, CKRL1, ChemR1, CDw198, CD198, CCR-8, CCR8
Catalog No. TMPK-00897 Copy Product Info
CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 30.25 kDa and the accession number is P51685-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $58 | - | In Stock | |
| 10 μg | $92 | - | In Stock | |
| 20 μg | $148 | 7-10 days | 7-10 days | |
| 50 μg | $289 | 7-10 days | 7-10 days | |
| 100 μg | $487 | 7-10 days | 7-10 days | |
| 200 μg | $883 | 7-10 days | 7-10 days | |
| 500 μg | $1,950 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human CCR8, mFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 11.1ng/ml determined by ELISA. |
| Description | CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 30.25 kDa and the accession number is P51685-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-mFc |
| Accession Number | P51685-1 |
| Construction | Met1-Lys35 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | TER-1, TER1, GPR-CY6, GPRCY6, CY6, CMKBRL2, CMKBR8, CKR-L1, CKRL1, ChemR1, CDw198, CD198, CCR-8, CCR8 |
| Research Background |
| Molecular Weight | 30.25 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: CCR8 Protein, Human, Recombinant (mFc) chemical structure | CCR8 Protein, Human, Recombinant (mFc) molecular weight
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