Shopping Cart

Your shopping cart is currently empty

Prim-O-glucosylcimifugin

Name: Prim-O-glucosylcimifugin
Brand: TargetMol
SKU: T3805
Price: 55 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

🥰Excellent

Catalog No. T3805Cas No. 80681-45-4

Alias Cimifugin beta-D-glucopyranoside, Cimifugin 7-glucoside

Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.

Prim-O-glucosylcimifugin

Copy Product Info

🥰Excellent

Purity: 99.92%

Catalog No. T3805Alias Cimifugin beta-D-glucopyranoside, Cimifugin 7-glucosideCas No. 80681-45-4

Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$55	In Stock	In Stock
5 mg	$122	In Stock	In Stock
10 mg	$222	In Stock	In Stock
25 mg	$375	In Stock	In Stock
50 mg	$553	In Stock	In Stock
100 mg	$789	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$126	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.92%

Color:White

Resource Download

COA

Product Introduction

Prim-O-glucosylcimifugin AI Summary

Prim-O-glucosylcimifugin exhibits a range of bioactivities including inhibition of ELG1-dependent DNA repair in human embryonic kidney cells, inhibition of HP1-beta chromodomain interactions with methylated histone tails, and activity as a substrate of mammalian selenoprotein thioredoxin reductase 1. Additionally, Prim-O-glucosylcimifugin shows inhibitory activity against the human IDH1 enzyme, specifically targeting the R132H mutant variant expressed in Escherichia coli BL21 cells. It demonstrates 111.8% activity in inhibiting the oxidation of NADPH to NADP+ and 96.8% activity in inhibiting the reduction of NADP+ to NADPH, as assessed by spectrophotometry after a 5-minute incubation..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase.
Synonyms	Cimifugin beta-D-glucopyranoside, Cimifugin 7-glucoside

Chemical Properties

Molecular Weight	468.45
Formula	C₂₂H₂₈O₁₁
Cas No.	80681-45-4
Smiles	COc1c2C[C@H](Oc2cc2oc(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc(=O)c12)C(C)(C)O
Relative Density.	1.538g/cm3

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (266.84 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.27 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1347 mL	10.6735 mL	21.3470 mL	106.7350 mL
5 mM	0.4269 mL	2.1347 mL	4.2694 mL	21.3470 mL
10 mM	0.2135 mL	1.0673 mL	2.1347 mL	10.6735 mL
20 mM	0.1067 mL	0.5337 mL	1.0673 mL	5.3367 mL
50 mM	0.0427 mL	0.2135 mL	0.4269 mL	2.1347 mL
100 mM	0.0213 mL	0.1067 mL	0.2135 mL	1.0673 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc