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IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-00162
Synonyms: Hematopoietin-1, Interleukin-1 Alpha, IL-1 α, IL1A, IL1F1, Interleukin-1 α, IL-1 Alpha

Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg In stock $ 118.00
50 μg 5 days $ 545.00
500 μg 5 days $ 2,530.00
1 mg 5 days $ 3,790.00
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Biological Description
Technical Params
Product Properties
Description Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.
Species Human
Expression System Human Cells
Tag C-Fc
Accession Number P01583
Synonyms Hematopoietin-1, Interleukin-1 Alpha, IL-1 α, IL1A, IL1F1, Interleukin-1 α, IL-1 Alpha
Amino Acid Ser113-Ala271
Construction Recombinant Human Interleukin-1 alpha is produced by our Mammalian expression system and the target gene encoding Ser113-Ala271 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

Molecular Weight 54 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.

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Keywords

IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) Hematopoietin-1 Interleukin-1 Alpha IL-1 α IL1A IL1F1 Interleukin-1 α IL-1 Alpha recombinant recombinant-proteins proteins protein

 

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