Home Tools
Log in
Cart

NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

Catalog No. TMPY-05414
Synonyms: D6H12S2489E, NKG2-D, killer cell lectin-like receptor subfamily K, member 1, Nkg2d

NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
100 μg In stock $ 386.00
200 μg 5 days $ 682.00
500 μg 5 days $ 1,440.00
Bulk Inquiry
Get quote
Select Batch  
Contact us for more batch information
Biological Description
Technical Params
Product Properties
References and Literature
Biological Information Testing in progress
Description NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
Species Mouse
Expression System Baculovirus Insect Cells
Tag N-hFc
Accession Number O54709-2
Synonyms D6H12S2489E, NKG2-D, killer cell lectin-like receptor subfamily K, member 1, Nkg2d
Construction The Mouse KLRK1 (NP_001076791.1) (Phe77-Val219) was expressed with the Fc region of Human IgG1 at the N-terminus.
Protein Purity > 90 % as determined by SDS-PAGE.

Molecular Weight 44.9 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 250 mM NaCl, pH 8.0, 10% glycerol. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stimulatory signals to activate CD8 T cells. NKG2D also plays an important role in viral control. Cellular stress can induce ligands for NKG2D which results in the cell susceptible to NK cell-mediated lysis.

References and Literature

Calculator

Reconstitution Calculator
Recombinant Proteins Dilute Calculator
Specific Activity Calculator
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

NKG2D/CD314 Protein, Mouse, Recombinant (hFc) D6H12S2489E NKG2-D killer cell lectin-like receptor subfamily K, member 1 Nkg2d recombinant recombinant-proteins proteins protein

 

TargetMol