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Anti-NF-kB p65 Antibody (8C70) is a Mouse antibody targeting NF-kB p65. Anti-NF-kB p65 Antibody (8C70) can be used in ELISA.
| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 100 μL | $198 | 7-10 days | 
| Description | Anti-NF-kB p65 Antibody (8C70) is a Mouse antibody targeting NF-kB p65. Anti-NF-kB p65 Antibody (8C70) can be used in ELISA.  | 
| Synonyms | v-rel avian reticuloendotheliosis viral oncogene homolog A, p65, NFKB3 | 
| Ig Type | Mouse IgG2b  | 
| Clone | 8C70  | 
| Reactivity | Human  | 
| Specificity | Human RELA/NF-kappa B p65 No cross-reactivity in ELISA with E.coli cell lysate  | 
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000  | 
| Antibody Type | Monoclonal  | 
| Host Species | Mouse | 
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RELA / Transcription factor p65 (rh RELA / Transcription factor p65; TMPY-02387; Q04206-1; Met 1-Tyr 306). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. | 
| Purification | Protein A | 
| Appearance | Liquid | 
| Formulation | 0.2 μm filtered solution in PBS | 
| Research Background | RELA (v-rel reticuloendotheliosis viral oncogene homolog A), also known as Nuclear factor NF-kappa-B p65 subunit, or Transcription factor p65, is a transcription factor expressed in growth plate chondrocytes where it facilitates chondrogenesis. The v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) gene encodes the major component of the NF-?B complex. NF-kappaB is a generic name for an evolutionarily conserved transcription-factor system that contributes to the mounting of an effective immune response but is also involved in the regulation of cell proliferation, development, and apoptosis. The implication of NF-kappaB in central biological processes and its extraordinary connectivity to other signaling pathways raise a need for highly controlled regulation of NF-kappaB activity at several levels. The mammalian Rel/NF-kappaB family of transcription factors, including RelA, c-Rel, RelB, NF-kappaB1 (p50 and its precursor p105), and NF-kappaB2 (p52 and its precursor p100), plays a central role in the immune system by regulating several processes ranging from the development and survival of lymphocytes and lymphoid organs to the control of immune responses and malignant transformation. | 
| Conjucates | Unconjugated  | 
| Immunogen | Recombinant Protein: Human RELA / Transcription factor p65 protein (TMPY-02387)  | 
| Antigen Species | Human  | 
| Biology Area | Apoptosis Transcription Factors and Regulators  | 
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. | 
| Transport | Shipping with blue ice. | 

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