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Anti-S100A8 Antibody (9G571)
😃Good
Catalog No. TMAY-01681
Alias S100a8, p8, MRP8, CP-10, CFAg, Caga, B8Ag, 60B8Ag
Anti-S100A8 Antibody (9G571) is a Rabbit antibody targeting S100A8. Anti-S100A8 Antibody (9G571) can be used in IHC-P.
Anti-S100A8 Antibody (9G571)
Anti-S100A8 Antibody (9G571)
😃Good
Catalog No. TMAY-01681Alias S100a8, p8, MRP8, CP-10, CFAg, Caga, B8Ag, 60B8Ag
Anti-S100A8 Antibody (9G571) is a Rabbit antibody targeting S100A8. Anti-S100A8 Antibody (9G571) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-S100A8 Antibody (9G571) is a Rabbit antibody targeting S100A8. Anti-S100A8 Antibody (9G571) can be used in IHC-P. |
| Alias | S100a8, p8, MRP8, CP-10, CFAg, Caga, B8Ag, 60B8Ag |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9G571 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human S100A8 in human tonsil with rabbit monoclonal antibody at 1:20000 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human S100A8 in human breast carcinoma with rabbit monoclonal antibody at 1:20000 dilution, formalin-fixed paraffin embedded sections. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:2000-1:50000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human S100A8 (rh S100A8; TMPY-01356; NP_002955.2; Met1-Glu93). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | S100A8 is a member of the S100 protein family containing 2EF-hand calcium-binding motifs. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of S100A8 protein is associated with various diseases and cancers. S100A8 may have an immunoregulatory role by contributing to the regulation of fetal-maternal interactions. It may play a protective role and its absence may allow infiltration by maternal cells, a process eventually manifesting as resorption. The heterodimeric S100 protein complex S100A8/A9 which has been shown to be involved in inflammatory and neoplastic disorders. The complex can induce cell proliferation, or apoptosis, inflammation, collagen synthesis, and cell migration. S100A8/A9 has emerged as important pro-inflammatory mediator in acute and chronic inflammation. More recently, increased S100A8 and S100A9 levels were also detected in various human cancers, presenting abundant expression in neoplastic tumor cells as well as infiltrating immune cells. On the one hand, S100A8/A9 is a powerful apoptotic agent produced by immune cells, making it a very fascinating tool in the battle against cancer. It spears the risk to induce auto-immune response and may serve as a lead compound for cancer-selective therapeutics. In contrast, S100A8/A9 expression in cancer cells has also been associated with tumor development, cancer invasion or metastasis. Altogether, its expression and potential cytokine-like function in inflammation and cancer suggest that S100A8/A9 may play a key role in inflammation-associated cancer. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human S100A8 Protein (TMPY-01356) |
| Antigen Species | Human |
| Biology Area | Calcium-binding Proteins and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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