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Anti-PDGF R alpha/PDGFRA Antibody (8H467) is a Rabbit antibody targeting PDGF R alpha/PDGFRA. Anti-PDGF R alpha/PDGFRA Antibody (8H467) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $273 | 7-10 days | |
100 μL | $487 | 7-10 days |
Description | Antibody Type: Recombinant Rabbit Monoclonal Application: WB Reactivity: Human,Mouse,Rat |
Ig Type | IgG |
Clone | 8H467 |
Reactivity | Human,Mouse,Rat |
Verified Activity | 25 μg total protein per Lane of various lysates probed with PDGFR alpha monoclonal antibody, unconjugated (TMAB-01349) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
Application | WB |
Recommended Dose | WB: 1:1000-2000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Note=The activated receptor is rapidly internalized and degraded. |
Construction | Recombinant Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]. |
Immunogen | A synthesized peptide: human PDGFR alpha |
Antigen Species | Human |
Gene ID | 5156 |
Uniprot ID | |
Biology Area | PDGF,Growth factor receptors,Growth Factors,Inflammatory mediators,PDGF,Receptor Tyrosine Kinases |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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