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Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody (Alias: Transforming growth factor-beta-activated kinase 1, T...)
Catalog No. TMAC-03957 Copy Product Info
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Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TAK1 (Thr184). Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody can be used in WB.
Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAC-03957
Alias Transforming growth factor-beta-activated kinase 1, TGF-beta-activated kinase 1, TGF1a, TGF beta activated kinase 1, TAK1 (p-Thr184), TAK1 (p-T184), TAK1, p-TAK1 (Thr184), p-TAK1 (T184), Mitogen-activated protein kinase kinase kinase 7, MEKK7, MAPKKK7, Map3k7, MAP3K 7, M3K7
Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TAK1 (Thr184). Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody can be used in WB.
Anti-Phospho-TAK1
(Thr184) Polyclonal Antibody
(Thr184) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $218 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TAK1 (Thr184). Anti-Phospho-TAK1 (Thr184) Polyclonal Antibody can be used in WB. |
| Synonyms | Transforming growth factor-beta-activated kinase 1, TGF-beta-activated kinase 1, TGF1a, TGF beta activated kinase 1, TAK1 (p-Thr184), TAK1 (p-T184), TAK1, p-TAK1 (Thr184), p-TAK1 (T184), Mitogen-activated protein kinase kinase kinase 7, MEKK7, MAPKKK7, Map3k7, MAP3K 7, M3K7 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from HepG2 cells, treated with TNF (20ng/ml, 5mins), using TAK1 (Phospho-Thr184) antibody TMAC-03957. The lane on the right is treated with the synthesized peptide. 2. Western blot analysis of extracts from 293 cells (Lane 2), using TAK1 (Phospho-Thr184) Antibody TMAC-03957. The lane on the left is treated with synthesized peptide.   |
| Application | |
| Recommended Dose | WB: 1:500-3000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 184 (I-Q-T(p)-H-M) derived from Human TAK1 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 65 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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