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Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody
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Catalog No. TMAC-00181
Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AMPK β1 (Ser181). Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody can be used in WB.
Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody
Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody
😃Good
Catalog No. TMAC-00181
Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AMPK β1 (Ser181). Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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| Description | Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AMPK β1 (Ser181). Anti-Phospho-AMPK β1 (Ser181) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine 181 (L-S-S(p)-S-P) derived from Human AMPK β1 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 38 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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