FGF-21 Protein, Mouse, Recombinant (His)

Name: FGF-21 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-02139
Price: 61 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: fibroblast growth factor 21, FGF-21) Copy Product Info

Synonyms: fibroblast growth factor 21, FGF-21

Catalog No. TMPY-02139 Copy Product Info

FGF-21 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is Q9JJN1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$61	-	In Stock
10 µg	$96	-	In Stock
20 µg	$157	-	In Stock
50 µg	$306	-	In Stock
100 µg	$515	7-10 days	7-10 days
200 µg	$873	7-10 days	7-10 days
500 µg	$1,760	7-10 days	7-10 days
1 mg	$3,000	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:93%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	FGF-21 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is Q9JJN1.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q9JJN1
Construction	A DNA sequence encoding the mouse FGF21 (Q9JJN1) (Met 1-Ser 210) was expressed, with a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 29
Protein Purity	> 85 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	fibroblast growth factor 21, FGF-21
Research Background	Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic properties in animal models of diabetes and obesity. FGF21 is a novel adipokine associated with obesity-related metabolic complications in humans. The paradoxical increase of serum FGF21 in obese individuals, which may be explained by a compensatory response or resistance to FGF21, warrants further investigation. FGF-21, which we have identified as a novel metabolic factor, exhibits the therapeutic characteristics necessary for an effective treatment of diabetes.

Chemical Properties

Molecular Weight

21.3 kDa (predicted); 25 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.