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Anti-MMP-3 Antibody (1U270)
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Catalog No. TMAY-00867
Alias STR1, STMY1, STMY, SL-1, MMP-3, matrix metallopeptidase 3, CHDS6
Anti-MMP-3 Antibody (1U270) is a Rabbit antibody targeting MMP-3. Anti-MMP-3 Antibody (1U270) can be used in ELISA.
Anti-MMP-3 Antibody (1U270)
Anti-MMP-3 Antibody (1U270)
😃Good
Catalog No. TMAY-00867Alias STR1, STMY1, STMY, SL-1, MMP-3, matrix metallopeptidase 3, CHDS6
Anti-MMP-3 Antibody (1U270) is a Rabbit antibody targeting MMP-3. Anti-MMP-3 Antibody (1U270) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-MMP-3 Antibody (1U270) is a Rabbit antibody targeting MMP-3. Anti-MMP-3 Antibody (1U270) can be used in ELISA. |
| Alias | STR1, STMY1, STMY, SL-1, MMP-3, matrix metallopeptidase 3, CHDS6 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1U270 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human MMP-3 / MMP3 (rh MMP-3 / MMP3; TMPY-02689; AAA36321.1; Tyr18-Thr272). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This protein is activated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMP3 plays a central role in degrading collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. Also, MMP3 can active other MMPs such as MMP1, MMP7, and MMP9, rendering MMP3 crucial in connective tissue remodeling. Dysregulation of MMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis, and cancer. Synthetic or natural inhibitors of MMPs result in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human MMP-3 / MMP3 Protein (TMPY-02689) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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