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Anti-Adenylate kinase 2 Antibody (1Z160)
🥰Excellent
Catalog No. TMAY-02505
Anti-Adenylate kinase 2 Antibody (1Z160) is a Rabbit antibody targeting Adenylate kinase 2. Anti-Adenylate kinase 2 Antibody (1Z160) can be used in WB,ELISA,IHC-P.
Anti-Adenylate kinase 2 Antibody (1Z160)
Anti-Adenylate kinase 2 Antibody (1Z160)
🥰Excellent
Catalog No. TMAY-02505
Anti-Adenylate kinase 2 Antibody (1Z160) is a Rabbit antibody targeting Adenylate kinase 2. Anti-Adenylate kinase 2 Antibody (1Z160) can be used in WB,ELISA,IHC-P.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Adenylate kinase 2 Antibody (1Z160) is a Rabbit antibody targeting Adenylate kinase 2. Anti-Adenylate kinase 2 Antibody (1Z160) can be used in WB,ELISA,IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1Z160 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human AK2 in human liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human AK2 in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Anti-AK2 rabbit monoclonal antibody at 1:500 dilution. -Lane A: Mouse kidney tissue Lysate. -Lane B: HCT116 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:26 kDa. -Observed band size:26 kDa |
| Application | WB,ELISA,IHC-P |
| Recommended Dose | WB: 1:500-1:2000; ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human AK2 (rh AK2; P54819-1Met1-Ile239). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Adenylate kinase 2 (AK2) belongs to the Adenylate kinase family that contains three isozymes: AK1, AK2 and AK3. Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Adenylate kinase2 (AK2) is expressed in mitochondrial intermembrane space. It may play a role in apoptosis. It has been demonstrated that in apoptotic cells AK2 was translocated into the cytosol concomitantly with cytochronme C. Mutations in this gene are the cause of reticular dysgenesis. These mutations result in absent or strongly decreased protein expression. It has been also established that AK2 is specifically expressed in the stria vascularis region of the inner ear, which provides an explanation of the sensorineural deafness in these individuals. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human AK2 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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