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Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody
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Catalog No. TMAC-03617
Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ROCK2 (Tyr722). Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody can be used in WB.
Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody
Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody
😃Good
Catalog No. TMAC-03617
Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ROCK2 (Tyr722). Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ROCK2 (Tyr722). Anti-Phospho-ROCK2 (Tyr722) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine 722 (K-I-Y(p)-E-S) derived from Human ROCK2 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 160 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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