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MitoPerOx

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Catalog No. T35963Cas No. 1392820-50-6

MitoPerOx is a ratiometric fluorescent probe that can be used to assess changes in lipid peroxidation within mitochondria. It is composed of a BODIPY fluorophore conjugated via a dienyl link to a triphenylphosphonium cation component that drives its accumulation in mitochondria. MitoPerOx displays an excitation maximum of 495 nm and exhibits a shift in emission maxima from 590 to 520 nm upon mitochondrial lipid peroxidation, enabling determination of ratiometric measurements of lipid peroxidation in live cells.

MitoPerOx

MitoPerOx

😃Good
Purity: 97.18%
Catalog No. T35963Cas No. 1392820-50-6
MitoPerOx is a ratiometric fluorescent probe that can be used to assess changes in lipid peroxidation within mitochondria. It is composed of a BODIPY fluorophore conjugated via a dienyl link to a triphenylphosphonium cation component that drives its accumulation in mitochondria. MitoPerOx displays an excitation maximum of 495 nm and exhibits a shift in emission maxima from 590 to 520 nm upon mitochondrial lipid peroxidation, enabling determination of ratiometric measurements of lipid peroxidation in live cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$455-In Stock
5 mg$1,130-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:97.18%
Appearance:Solid
Color:Purple
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Product Introduction

Bioactivity
Description
MitoPerOx is a ratiometric fluorescent probe that can be used to assess changes in lipid peroxidation within mitochondria. It is composed of a BODIPY fluorophore conjugated via a dienyl link to a triphenylphosphonium cation component that drives its accumulation in mitochondria. MitoPerOx displays an excitation maximum of 495 nm and exhibits a shift in emission maxima from 590 to 520 nm upon mitochondrial lipid peroxidation, enabling determination of ratiometric measurements of lipid peroxidation in live cells.
Chemical Properties
Molecular Weight760.47
FormulaC42H38BBrF2N3OP
Cas No.1392820-50-6
SmilesO=C(CCC1=CC=C2C=C3C=CC(C=CC=CC4=CC=CC=C4)=[N+]3[B-](F)(N21)F)NCC[P+](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7.[Br-]
Storage & Solubility Information
Storagekeep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (131.5 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3150 mL6.5749 mL13.1498 mL65.7488 mL
5 mM0.2630 mL1.3150 mL2.6300 mL13.1498 mL
10 mM0.1315 mL0.6575 mL1.3150 mL6.5749 mL
20 mM0.0657 mL0.3287 mL0.6575 mL3.2874 mL
50 mM0.0263 mL0.1315 mL0.2630 mL1.3150 mL
100 mM0.0131 mL0.0657 mL0.1315 mL0.6575 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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