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Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)
(Synonyms: interferon, α1, interferon, alpha 1, Interferon α1, IFN-αD, IFN-α, IFN-alphaD, IFN-ALPHA, IFNA13, IFNA@, IFN, IFL) Copy Product InfoSynonyms: interferon, α1, interferon, alpha 1, Interferon α1, IFN-αD, IFN-α, IFN-alphaD, IFN-ALPHA, IFNA13, IFNA@, IFN, IFL
Catalog No. TMPY-04578 Copy Product Info
Purity: 98.3%
Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.8 kDa and the accession number is L0N195.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $44 | - | In Stock | |
| 10 µg | $68 | - | In Stock | |
| 20 µg | $108 | - | In Stock | |
| 50 µg | $198 | - | In Stock | |
| 100 µg | $346 | - | In Stock | |
| 200 µg | $593 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.3%
Appearance:Lyophilized powder
Color:White
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Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured in antiviral assays using WISH cells infected with vesicular stomatitis virus. The ED50 for this effect is 40-200pg/mL. |
| Description | Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.8 kDa and the accession number is L0N195. |
| Species | Human |
| Expression System | P. pastoris (Yeast) |
| Tag | C-His |
| Accession Number | L0N195 |
| Construction | A DNA sequence encoding the human IFNA1 (NP_076918.1) (Cys24-Glu189) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Cys 24 |
| Protein Purity | > 95 % as determined by SDS-PAGE  |
| Endotoxin | Please contact us for more information. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | interferon, α1, interferon, alpha 1, Interferon α1, IFN-αD, IFN-α, IFN-alphaD, IFN-ALPHA, IFNA13, IFNA@, IFN, IFL |
| Research Background | IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they also increase the ability of uninfected host cells to resist new infection by the virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Molecular Weight | 20.8 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) chemical structure | Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) molecular weight
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