Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)

Catalog No. TMPY-04578 Copy Product Info

Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.8 kDa and the accession number is L0N195.

Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)

Catalog No. TMPY-04578

Copy Product Info

Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.8 kDa and the accession number is L0N195.

Pack Size	Price	USA Stock	Global Stock
5 μg	$44	7-10 days	7-10 days
10 μg	$68	7-10 days	7-10 days
20 μg	$108	7-10 days	7-10 days
50 μg	$198	7-10 days	7-10 days
100 μg	$346	-	In Stock
200 μg	$593	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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COA User Guide of Recombinant Proteins

Product Information

Biological Activity	Measured in antiviral assays using WISH cells infected with vesicular stomatitis virus. The ED50 for this effect is 40-200pg/mL.
Description	Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.8 kDa and the accession number is L0N195.
Species	Human
Expression System	P. pastoris (Yeast)
Tag	C-His
Accession Number	L0N195
Synonyms	interferon, α1,interferon, alpha 1,Interferon α1,IFN-αD,IFN-α,IFN-alphaD,IFN-ALPHA,IFNA13,IFNA@,IFN,IFL
Construction	A DNA sequence encoding the human IFNA1 (NP_076918.1) (Cys24-Glu189) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Cys 24
Protein Purity	> 95 % as determined by SDS-PAGE
Molecular Weight	20.8 kDa (predicted)
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they also increase the ability of uninfected host cells to resist new infection by the virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy