CD40 Ligand Protein, Human, Recombinant (Mammalian)

Name: CD40 Ligand Protein, Human, Recombinant (Mammalian)
Brand: TargetMol
SKU: TMPJ-00150
Rating: 4.5 (1 reviews)

(Synonyms: Tumor Necrosis Factor Ligand Superfamily Member 5, TRAP, TNFSF5, TNF-Related Activation Protein, T-Cell Antigen Gp39, CD40LG, CD40-L, CD40L, CD40 Ligand, CD154) Copy Product Info

Synonyms: Tumor Necrosis Factor Ligand Superfamily Member 5, TRAP, TNFSF5, TNF-Related Activation Protein, T-Cell Antigen Gp39, CD40LG, CD40-L, CD40L, CD40 Ligand, CD154

Catalog No. TMPJ-00150 Copy Product Info

CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number is P29965.

Pack Size	Price	USA Stock	Global Stock
5 µg	$72	7-10 days	7-10 days
10 µg	$116	7-10 days	7-10 days
20 µg	$176	7-10 days	7-10 days
50 µg	$310	7-10 days	7-10 days
100 µg	$532	7-10 days	7-10 days
200 µg	$919	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:Greater than 95% as determined by reducing SDS-PAGE.Greater than 95% as determined by SEC-HPLC. (QC verified)

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1. Loaded Human CD40-mFc on AMC Biosensor, can bind Human CD40L with an affinity constant of 10.2 nM as determined in BLI assay. (Regularly tested) 2. Loaded Human CD40-Fc on Protein A Biosensor, can bind Human CD40L with an affinity constant of 3.29
Description	CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number is P29965.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	P29965
Amino Acid	Met113-Leu261
Construction	Met113-Leu261
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 200 mM NaCl, 0.1 mM EDTA, pH 7.0.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Tumor Necrosis Factor Ligand Superfamily Member 5, TRAP, TNFSF5, TNF-Related Activation Protein, T-Cell Antigen Gp39, CD40LG, CD40-L, CD40L, CD40 Ligand, CD154
Research Background	CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer in membrane bound and soluble form, both of which are bioactive. CD40LG is a ligand for CD40; its ligation also initiates signal transduction in CD40LG expressing cells. CD40LG is a differentiation antigen that is expressed on the surface of T-cells. It stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2.

Chemical Properties

Molecular Weight

16-18 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Tech Support

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Keywords

TNFSF-5TNFSF 5CD-154CD 154

Related Tags: CD40 Ligand Protein, Human, Recombinant (Mammalian) chemical structure | CD40 Ligand Protein, Human, Recombinant (Mammalian) molecular weight