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Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
(Synonyms: Transforming growth factor β-3, Transforming growth factor beta-3 proprotein, TGF-β-3, TGFβ3, TGF-beta-3, TGFB3, Latent TGF-β3) Copy Product InfoSynonyms: Transforming growth factor β-3, Transforming growth factor beta-3 proprotein, TGF-β-3, TGFβ3, TGF-beta-3, TGFB3, Latent TGF-β3
Catalog No. TMPJ-00256 Copy Product Info
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 12 and 37-45 KDa and the accession number is P10600.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $318 | 35 days | 35 days | |
| 10 µg | $533 | 35 days | 35 days | |
| 20 µg | $900 | 35 days | 35 days | |
| 50 µg | $1,580 | 35 days | 35 days | |
| 100 µg | $2,480 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 12 and 37-45 KDa and the accession number is P10600. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-8xHis-Avi |
| Accession Number | P10600 |
| Amino Acid | Leu30-Ser390 |
| Construction | Leu30-Ser390 (Cys33Ser) |
| Protein Purity | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | Transforming growth factor β-3, Transforming growth factor beta-3 proprotein, TGF-β-3, TGFβ3, TGF-beta-3, TGFB3, Latent TGF-β3 |
| Research Background | Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. TGF-beta 3 binds with high affinity to TGF-beta RII, a type II serine/threonine kinase receptor. This receptor then phosphorylates and activates type I serine/threonine kinase receptors, TGF-beta RI or ALK-1, to modulate transcription through Smad phosphorylation. |
| Molecular Weight | 12&37-45 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight
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